186390-35-2

186390-35-2 structure
186390-35-2 structure
  • Name: CP-319340(free base)
  • Chemical Name: CP-319340(free base)
  • CAS Number: 186390-35-2
  • Molecular Formula: C27H23F3N4O
  • Molecular Weight: 476.49
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-03-19 14:09:34
  • Modify Date: 2025-08-25 15:51:42
  • CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

Name CP-319340(free base)
Description CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.
Related Catalog
Target

MTP[1][2]

In Vitro Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB[3].
References

[1]. Sugi, Kiyoshi, et al. Process for producing 4-(2-methylphenyl)benzotrifluoride. EP1700837A1.

[2]. Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1.

[3]. Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44(1):22-32.

Molecular Formula C27H23F3N4O
Molecular Weight 476.49
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