390808-64-7
390808-64-7 structure
- Name: MSI-1701
- Chemical Name: MSI-1701
- CAS Number: 390808-64-7
- Molecular Formula: C37H72N4O5S
- Molecular Weight: 685.06
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-02-03 03:52:33
- Modify Date: 2024-01-09 18:05:06
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MSI-1701 is an analogue of MSI-1436 which can control weight gain and blood glucose level extracted from patent US 7410959 B1.
| Name | MSI-1701 |
|---|
| Description | MSI-1701 is an analogue of MSI-1436 which can control weight gain and blood glucose level extracted from patent US 7410959 B1. |
|---|---|
| Related Catalog | |
| In Vivo | Analogues that differ from MSI-1436 at only a single stereocenter, such as MSI-1701 (the polyamine at C-3) or MSI-1777 (the methyl at C-20) exhibit significantly reduced activity, while MSI-1673 (the OH at C-7) is completely inactive[1]. |
| Animal Admin | Experiments are performed using age-matched (4 to 5 weeks old) male mice provided food and water ad lib. Mice corresponding to a single experimental cohort are housed together in a single cage. Animals are used 1 week after arrival. Drug dosing is conducted with 10 mg/kg of each compound (including MSI-1701) via the i.p. route every 3 days for 4 doses, beginning on day 0[1]. |
| References |
[1]. Michael Zasloff, et al. Therapeutic uses for aminosterol compounds. US 7410959 B1. |
| Molecular Formula | C37H72N4O5S |
|---|---|
| Molecular Weight | 685.06 |
| Storage condition | 2-8℃ |