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  • DC Chemicals Limited
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  • Product Name: YH16899
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  • Purity: 98.0%
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  • Contact: Tony Cao

1428623-14-6

1428623-14-6 structure
1428623-14-6 structure
  • Name: YH16899
  • Chemical Name: 2-[(2Z)-5,6-Difluoro-2-{[3-(trifluoromethyl)benzoyl]imino}-1,3-benzothiazol-3(2H)-yl]butanoic acid
  • CAS Number: 1428623-14-6
  • Molecular Formula: C19H13F5N2O3S
  • Molecular Weight: 444.375
  • Catalog: Research Areas Cancer
  • Create Date: 2018-06-15 13:45:21
  • Modify Date: 2024-01-10 17:40:22
  • YH16899 binds Lysyl-tRNA synthetase (KRS), and inhibits membrane translocation of KRS. YH16899 impares the interaction of KRS with 67LR. YH16899 inhibits tumor metastasis in mouse models[1].

Name 2-[(2Z)-5,6-Difluoro-2-{[3-(trifluoromethyl)benzoyl]imino}-1,3-benzothiazol-3(2H)-yl]butanoic acid
Synonyms 3(2H)-Benzothiazoleacetic acid, α-ethyl-5,6-difluoro-2-[[3-(trifluoromethyl)benzoyl]imino]-, (2Z)-
2-[(2Z)-5,6-Difluoro-2-{[3-(trifluoromethyl)benzoyl]imino}-1,3-benzothiazol-3(2H)-yl]butanoic acid
Description YH16899 binds Lysyl-tRNA synthetase (KRS), and inhibits membrane translocation of KRS. YH16899 impares the interaction of KRS with 67LR. YH16899 inhibits tumor metastasis in mouse models[1].
Related Catalog
References

[1]. Kim DG, et al. Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction. Nat Chem Biol. 2014 Jan;10(1):29-34.  

Density 1.5±0.1 g/cm3
Boiling Point 569.8±60.0 °C at 760 mmHg
Molecular Formula C19H13F5N2O3S
Molecular Weight 444.375
Flash Point 298.4±32.9 °C
Exact Mass 444.056702
LogP 5.08
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.593