956154-63-5

956154-63-5 structure

Name: TCS HDAC6 20b
Chemical Name: S-[(6S)-7-(Adamantan-1-ylamino)-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-7-oxoheptyl] 2-methylpropanethioate
CAS Number: 956154-63-5
Molecular Formula: C₂₆H₄₄N₂O₄S
Molecular Weight: 480.704
Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
Create Date: 2018-07-10 17:04:01
Modify Date: 2024-01-12 19:04:33
TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].

Name	S-[(6S)-7-(Adamantan-1-ylamino)-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-7-oxoheptyl] 2-methylpropanethioate
Synonyms	Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester S-[(6S)-7-(Adamantan-1-ylamino)-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-7-oxoheptyl] 2-methylpropanethioate S-[(6S)-6-[(tert-butoxycarbonyl)amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] 2-methylpropanethioate TCS HDAC6 20b

Description	TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Yukihiro Itoh, et al. Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007 Nov 1;50(22):5425-38.