160800-82-8
160800-82-8 structure
- Name: Dap-NE
- Chemical Name: (2R,3R)-N-[(1S,2R)-1-Hydroxy-1-phenyl-2-propanyl]-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanamide
- CAS Number: 160800-82-8
- Molecular Formula: C18H28N2O3
- Molecular Weight: 320.427
- Catalog: Research Areas Cancer
- Create Date: 2018-07-07 14:52:03
- Modify Date: 2025-08-22 09:46:04
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Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162)[1].
| Name | (2R,3R)-N-[(1S,2R)-1-Hydroxy-1-phenyl-2-propanyl]-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanamide |
|---|---|
| Synonyms |
2-Pyrrolidinepropanamide, N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-β-methoxy-α-methyl-, (αR,βR,2S)-
(2R,3R)-N-[(1S,2R)-1-Hydroxy-1-phenyl-2-propanyl]-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanamide |
| Description | Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 527.8±50.0 °C at 760 mmHg |
| Molecular Formula | C18H28N2O3 |
| Molecular Weight | 320.427 |
| Flash Point | 273.0±30.1 °C |
| Exact Mass | 320.209991 |
| LogP | 1.06 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.531 |