1365255-75-9

1365255-75-9 structure

Name: 4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine
Chemical Name: 1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione
CAS Number: 1365255-75-9
Molecular Formula: C₉H₉FN₂O₄
Molecular Weight: 228.18
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-06 00:00:03
Modify Date: 2024-04-09 20:33:49
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione
Synonyms	2,4(1H,3H)-Pyrimidinedione, 1-(2,5-dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)- 1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione

Description	4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.