4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine

Modify Date: 2024-04-09 20:33:49

4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine Structure
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine structure
Common Name 4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine
CAS Number 1365255-75-9 Molecular Weight 228.18
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H9FN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine


4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione
Synonym More Synonyms

  Biological Activity

Description 4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C9H9FN2O4
Molecular Weight 228.18
Exact Mass 228.054642
LogP -1.44
Index of Refraction 1.594

 Synonyms

2,4(1H,3H)-Pyrimidinedione, 1-(2,5-dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-
1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione