940005-81-2

940005-81-2 structure

Name: Bromoacetamido-PEG3-azide
Chemical Name: N-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethyl)-2-bromoacetamide
CAS Number: 940005-81-2
Molecular Formula: C₁₀H₁₉BrN₄O₄
Molecular Weight: 339.186
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-03 18:37:01
Modify Date: 2024-04-05 13:43:55
Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethyl)-2-bromoacetamide
Synonyms	N-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethyl)-2-bromoacetamide Acetamide, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-2-bromo-

Description	Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562