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54483-84-0

54483-84-0 structure
54483-84-0 structure
  • Name: 3α-Dihydrocadambine
  • Chemical Name: 3a-Dihydrocadambine
  • CAS Number: 54483-84-0
  • Molecular Formula: C27H34N2O10
  • Molecular Weight: 546.57
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-06-04 11:45:39
  • Modify Date: 2024-01-17 14:23:45
  • 3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats[1][2].

Name 3a-Dihydrocadambine
Synonyms 3α-Dihydrocadambine
Methyl (4S,4aS,5S,14bS,15aS)-4-(β-D-glucopyranosyloxy)-5-hydroxy-4,4a,5,6,8,9,14,14b,15,15a-decahydropyrano[4'',3'':4',5']azepino[1',2':1,2]pyrido[3,4-b]indole-1-carboxylate
Pyrano[4'',3'':4',5']azepino[1',2':1,2]pyrido[3,4-b]indole-1-carboxylic acid, 4-(β-D-glucopyranosyloxy)-4,4a,5,6,8,9,14,14b,15,15a-decahydro-5-hydroxy-, methyl ester, (4S,4aS,5S,14bS,15aS)-
3a-Dihydrocadambine
Description 3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats[1][2].
Related Catalog
References

[1]. Takayama H, et al. Gluco-indole alkaloids from Nauclea cadamba in Thailand and transformation of 3 alpha-dihydrocadambine into the indolopyridine alkaloid, 16-carbomethoxynaufoline. Chem Pharm Bull (Tokyo). 2003;51(2):232-233.  

[2]. K Aisaka, et al. Hypotensive action of 3 alpha-dihydrocadambine, an indole alkaloid glycoside of Uncaria hooks. Planta Med. 1985 Oct;51(5):424-7.  

Density 1.6±0.1 g/cm3
Boiling Point 802.9±65.0 °C at 760 mmHg
Melting Point 182-187 °C
Molecular Formula C27H34N2O10
Molecular Weight 546.57
Flash Point 439.4±34.3 °C
Exact Mass 546.221375
LogP -0.72
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.705
Hazard Codes Xi
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