1404559-91-6

1404559-91-6 structure

Name: BRD4884
Chemical Name: N-(4-Amino-4'-Fluoro[1,1'-Biphenyl]-3-Yl)oxane-4-Carboxamide
CAS Number: 1404559-91-6
Molecular Formula: C₁₈H₁₉FN₂O₂
Molecular Weight: 314.354
Create Date: 2018-06-08 09:42:19
Modify Date: 2022-05-07 23:05:58
BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively[1].

Name	N-(4-Amino-4'-Fluoro[1,1'-Biphenyl]-3-Yl)oxane-4-Carboxamide
Synonyms	N-(4-Amino-4'-fluoro-3-biphenylyl)tetrahydro-2H-pyran-4-carboxamide 2H-Pyran-4-carboxamide, N-(4-amino-4'-fluoro[1,1'-biphenyl]-3-yl)tetrahydro- N-(4-Amino-4'-Fluoro[1,1'-Biphenyl]-3-Yl)oxane-4-Carboxamide

Description	BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Research Areas >> Neurological Disease Signaling Pathways >> Epigenetics >> HDAC
Target	HDAC1:29 nM (IC50) HDAC2:62 nM (IC50) HDAC3:1.09 μM (IC50)
References	[1]. Wagner FF, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chem Sci. 2015 Jan 1;6(1):804-815.