Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Boc-NH-PEG12-CH2CH2COOH
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Purity: 98.0%
Stocking Period: 10 Day
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1415981-79-1

1415981-79-1 structure

1415981-79-1 structure

Name: Boc-NH-PEG12-CH2CH2COOH
Chemical Name: 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35,38,41-tridecaoxa-5-azatetratetracontan-44-oic acid
CAS Number: 1415981-79-1
Molecular Formula: C₃₂H₆₃NO₁₆
Molecular Weight: 717.840
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-12 12:19:51
Modify Date: 2025-08-27 15:02:02
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35,38,41-tridecaoxa-5-azatetratetracontan-44-oic acid
Synonyms	3,8,11,14,17,20,23,26,29,32,35,38,41-Tridecaoxa-5-azatetratetracontan-44-oic acid, 2,2-dimethyl-4-oxo- MFCD13185149 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35,38,41-tridecaoxa-5-azatetratetracontan-44-oic acid

Description	Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.1±0.1 g/cm3
Boiling Point	736.3±60.0 °C at 760 mmHg
Molecular Formula	C₃₂H₆₃NO₁₆
Molecular Weight	717.840
Flash Point	399.1±32.9 °C
Exact Mass	717.414673
LogP	-3.01
Vapour Pressure	0.0±5.2 mmHg at 25°C
Index of Refraction	1.469

Hazard Codes	Xi

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