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1807521-00-1

1807521-00-1 structure
1807521-00-1 structure
  • Name: Bromoacetamido-PEG4-C2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
  • CAS Number: 1807521-00-1
  • Molecular Formula: C17H32BrNO7
  • Molecular Weight: 442.342
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-08 06:51:15
  • Modify Date: 2024-03-07 12:58:00
  • Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
Synonyms MFCD28505519
2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
6,9,12,15-Tetraoxa-3-azaoctadecan-18-oic acid, 1-bromo-2-oxo-, 1,1-dimethylethyl ester
Description Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

Density 1.2±0.1 g/cm3
Boiling Point 539.3±50.0 °C at 760 mmHg
Molecular Formula C17H32BrNO7
Molecular Weight 442.342
Flash Point 280.0±30.1 °C
Exact Mass 441.136200
LogP 0.38
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.477
Storage condition 2-8°C