Bromoacetamido-PEG4-C2-Boc

Modify Date: 2024-03-07 12:58:00

Bromoacetamido-PEG4-C2-Boc Structure
Bromoacetamido-PEG4-C2-Boc structure
Common Name Bromoacetamido-PEG4-C2-Boc
CAS Number 1807521-00-1 Molecular Weight 442.342
Density 1.2±0.1 g/cm3 Boiling Point 539.3±50.0 °C at 760 mmHg
Molecular Formula C17H32BrNO7 Melting Point N/A
MSDS N/A Flash Point 280.0±30.1 °C

 Use of Bromoacetamido-PEG4-C2-Boc


Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
Synonym More Synonyms

 Bromoacetamido-PEG4-C2-Boc Biological Activity

Description Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 539.3±50.0 °C at 760 mmHg
Molecular Formula C17H32BrNO7
Molecular Weight 442.342
Flash Point 280.0±30.1 °C
Exact Mass 441.136200
LogP 0.38
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.477
Storage condition 2-8°C

 Synonyms

MFCD28505519
2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
6,9,12,15-Tetraoxa-3-azaoctadecan-18-oic acid, 1-bromo-2-oxo-, 1,1-dimethylethyl ester
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