Top Suppliers:I want be here



406213-76-1

406213-76-1 structure
406213-76-1 structure
  • Name: Azido-PEG6-C2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
  • CAS Number: 406213-76-1
  • Molecular Formula: C19H37N3O8
  • Molecular Weight: 435.512
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-04 05:48:32
  • Modify Date: 2024-01-08 14:45:42
  • Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Synonyms 2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 1,1-dimethylethyl ester
Description Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H37N3O8
Molecular Weight 435.512
Exact Mass 435.258057
LogP -0.09
Storage condition 2-8°C