Azido-PEG6-C2-Boc

Modify Date: 2024-01-08 14:45:42

Azido-PEG6-C2-Boc Structure
Azido-PEG6-C2-Boc structure
Common Name Azido-PEG6-C2-Boc
CAS Number 406213-76-1 Molecular Weight 435.512
Density N/A Boiling Point N/A
Molecular Formula C19H37N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG6-C2-Boc


Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Synonym More Synonyms

 Azido-PEG6-C2-Boc Biological Activity

Description Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H37N3O8
Molecular Weight 435.512
Exact Mass 435.258057
LogP -0.09
Storage condition 2-8°C

 Synonyms

2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 1,1-dimethylethyl ester
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