Azido-PEG6-C2-Boc

Modify Date: 2024-01-08 14:45:42

Use of Azido-PEG6-C2-Boc

Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Synonym	More Synonyms

Description	Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate

3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 1,1-dimethylethyl ester

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