155130-15-7

155130-15-7 structure

Name: PEG5-Tos
Chemical Name: 14-Hydroxy-3,6,9,12-tetraoxatetradec-1-yl 4-methylbenzenesulfonate
CAS Number: 155130-15-7
Molecular Formula: C₁₇H₂₈O₈S
Molecular Weight: 392.464
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-09 01:18:36
Modify Date: 2024-01-16 19:14:42
PEG5-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	14-Hydroxy-3,6,9,12-tetraoxatetradec-1-yl 4-methylbenzenesulfonate
Synonyms	3,6,9,12-Tetraoxatetradecane-1,14-diol, mono(4-methylbenzenesulfonate) 14-Hydroxy-3,6,9,12-tetraoxatetradec-1-yl 4-methylbenzenesulfonate

Description	PEG5-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.