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870487-09-5

870487-09-5 structure
870487-09-5 structure
  • Name: Boc-Val-Cit-PAB
  • Chemical Name: N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
  • CAS Number: 870487-09-5
  • Molecular Formula: C23H37N5O6
  • Molecular Weight: 479.570
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-26 02:47:57
  • Modify Date: 2024-01-05 14:49:54
  • Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
Synonyms L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
Description Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.2±0.1 g/cm3
Boiling Point 771.3±60.0 °C at 760 mmHg
Molecular Formula C23H37N5O6
Molecular Weight 479.570
Flash Point 420.3±32.9 °C
Exact Mass 479.274384
LogP 0.84
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.558
Storage condition 2-8°C