886469-23-4

886469-23-4 structure

Name: PEG9-Tos
Chemical Name: PEG8-Ts
CAS Number: 886469-23-4
Molecular Formula: C₂₃H₄₀O₁₁S
Molecular Weight: 524.622
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-10 01:23:09
Modify Date: 2024-01-12 19:32:28
PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	PEG8-Ts
Synonyms	23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl 4-methylbenzenesulfonate PEG8-Ts 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, mono(4-methylbenzenesulfonate) PEG8-OTs

Description	PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.