1187451-41-7

1187451-41-7 structure

Name: Omidenepag
Chemical Name: omidenepag
CAS Number: 1187451-41-7
Molecular Formula: C₂₃H₂₂N₆O₄S
Molecular Weight: 478.524
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2018-10-17 20:14:47
Modify Date: 2024-01-03 15:57:48
Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].

Name	omidenepag
Synonyms	UNII-Z95F9F9LU4 Z95F9F9LU4 UR-7276 Glycine, N-[6-[[[[4-(1H-pyrazol-1-yl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]-2-pyridinyl]- N-[6-({[4-(1H-Pyrazol-1-yl)benzyl](3-pyridinylsulfonyl)amino}methyl)-2-pyridinyl]glycine N-{6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}glycine omidenepag

Description	Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Target	EP2:1.1 nM (EC50) h-EP1:10 nM (IC50) h-EP4:5480 nM (IC50)
References	[1]. Iwamura R, et al. Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl. J Med Chem. 2018 Aug 9;61(15):6869-6891.