Omidenepag

Modify Date: 2024-01-03 15:57:48

Omidenepag Structure
Omidenepag structure
Common Name Omidenepag
CAS Number 1187451-41-7 Molecular Weight 478.524
Density 1.4±0.1 g/cm3 Boiling Point 769.4±70.0 °C at 760 mmHg
Molecular Formula C23H22N6O4S Melting Point N/A
MSDS N/A Flash Point 419.1±35.7 °C

 Use of Omidenepag


Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].

 Names

Name omidenepag
Synonym More Synonyms

 Omidenepag Biological Activity

Description Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2[1].
Related Catalog
Target

EP2:1.1 nM (EC50)

h-EP1:10 nM (IC50)

h-EP4:5480 nM (IC50)

References

[1]. Iwamura R, et al. Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl. J Med Chem. 2018 Aug 9;61(15):6869-6891.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 769.4±70.0 °C at 760 mmHg
Molecular Formula C23H22N6O4S
Molecular Weight 478.524
Flash Point 419.1±35.7 °C
Exact Mass 478.142334
LogP 1.75
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.680

 Synonyms

UNII-Z95F9F9LU4
Z95F9F9LU4
UR-7276
Glycine, N-[6-[[[[4-(1H-pyrazol-1-yl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]-2-pyridinyl]-
N-[6-({[4-(1H-Pyrazol-1-yl)benzyl](3-pyridinylsulfonyl)amino}methyl)-2-pyridinyl]glycine
N-{6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}glycine
omidenepag
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