1215767-66-0

1215767-66-0 structure
1215767-66-0 structure
  • Name: Ketorolac D5
  • Chemical Name: 5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • CAS Number: 1215767-66-0
  • Molecular Formula: C15H8D5NO3
  • Molecular Weight: 260.299
  • Catalog: Signaling Pathways Immunology/Inflammation COX
  • Create Date: 2018-07-06 06:46:48
  • Modify Date: 2025-08-27 13:53:20
  • Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1].

Name 5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Synonyms 1H-Pyrrolizine-1-carboxylic acid, 2,3-dihydro-5-(phenyl-d5-carbonyl)-
5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Description Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1].
Related Catalog
Target

COX-1:20 nM (IC50)

COX-2:120 nM (IC50)

References

[1]. Waterbury LD, et al. Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Curr Med Res Opin. 2006 Jun;22(6):1133-40.

Density 1.3±0.1 g/cm3
Boiling Point 493.2±40.0 °C at 760 mmHg
Molecular Formula C15H8D5NO3
Molecular Weight 260.299
Flash Point 252.1±27.3 °C
Exact Mass 260.120941
LogP 2.08
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.659
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