1262897-74-4

1262897-74-4 structure

Name: (2S)-Gemcitabine-13C,15N2 hydrochloride
Chemical Name: 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
CAS Number: 1262897-74-4
Molecular Formula: C₈₁₃CH₁₂ClF₂N₁₅N₂O₄
Molecular Weight: 302.639
Catalog: Research Areas Others
Create Date: 2018-06-04 06:17:38
Modify Date: 2024-01-10 15:21:45
(2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].

Name	4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
Synonyms	4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1) 2(1H)-Pyrimidinone-2-13C-1,3-15N2, 4-amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-, hydrochloride (1:1)

Description	(2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.