(2S)-Gemcitabine-13C,15N2 hydrochloride

Modify Date: 2024-01-10 15:21:45

(2S)-Gemcitabine-13C,15N2 hydrochloride structure	Common Name	(2S)-Gemcitabine-13C,15N2 hydrochloride
	CAS Number	1262897-74-4	Molecular Weight	302.639
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₁₃CH₁₂ClF₂N₁₅N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (2S)-Gemcitabine-13C,15N2 hydrochloride

(2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].

Name	4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
Synonym	More Synonyms

Description	(2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)

2(1H)-Pyrimidinone-2-13C-1,3-15N2, 4-amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-, hydrochloride (1:1)