1334172-58-5

1334172-58-5 structure
1334172-58-5 structure
  • Name: Biotin-PEG4-PFP ester
  • Chemical Name: Pentafluorophenyl 17-oxo-21-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13-tetraoxa-16-azahenicosan-1-oate
  • CAS Number: 1334172-58-5
  • Molecular Formula: C27H36F5N3O8S
  • Molecular Weight: 657.647
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-09 09:23:49
  • Modify Date: 2025-08-26 18:24:45
  • Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name Pentafluorophenyl 17-oxo-21-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13-tetraoxa-16-azahenicosan-1-oate
Synonyms Pentafluorophenyl 17-oxo-21-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13-tetraoxa-16-azahenicosan-1-oate
4,7,10,13-Tetraoxa-16-azaheneicosan-1-oic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, 2,3,4,5,6-pentafluorophenyl ester
Description Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.3±0.1 g/cm3
Boiling Point 804.9±65.0 °C at 760 mmHg
Molecular Formula C27H36F5N3O8S
Molecular Weight 657.647
Flash Point 440.6±34.3 °C
Exact Mass 657.214355
LogP 0.97
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.503
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