1654740-73-4
1654740-73-4 structure
- Name: Fmoc-NH-PEG1-C2-acid
- Chemical Name: 3-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)propanoic acid
- CAS Number: 1654740-73-4
- Molecular Formula: C20H21NO5
- Molecular Weight: 355.384
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-29 15:22:45
- Modify Date: 2024-01-11 15:15:16
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Fmoc-NH-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)propanoic acid |
|---|---|
| Synonyms |
MFCD16294357
Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]- 3-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)propanoic acid Fmoc-6-Amino-4-oxahexanoic acid |
| Description | Fmoc-NH-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 589.9±40.0 °C at 760 mmHg |
| Molecular Formula | C20H21NO5 |
| Molecular Weight | 355.384 |
| Flash Point | 310.6±27.3 °C |
| Exact Mass | 355.141968 |
| LogP | 3.37 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.589 |