133345-66-1
133345-66-1 structure
- Name: 6-Bromohexylphosphonic acid
- Chemical Name: (6-Bromohexyl)phosphonic acid
- CAS Number: 133345-66-1
- Molecular Formula: C6H14BrO3P
- Molecular Weight: 245.051
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-10 12:33:04
- Modify Date: 2024-01-28 20:19:37
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6-Bromohexylphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | (6-Bromohexyl)phosphonic acid |
|---|---|
| Synonyms |
Phosphonic acid, (6-bromohexyl)-
MFCD25424118 (6-Bromohexyl)phosphonic acid |
| Description | 6-Bromohexylphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 374.1±44.0 °C at 760 mmHg |
| Molecular Formula | C6H14BrO3P |
| Molecular Weight | 245.051 |
| Flash Point | 180.0±28.4 °C |
| Exact Mass | 243.986389 |
| LogP | 0.50 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.506 |