Top Suppliers:I want be here



1347750-75-7

1347750-75-7 structure
1347750-75-7 structure
  • Name: Boc-N-amido-PEG3-acid
  • Chemical Name: 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
  • CAS Number: 1347750-75-7
  • Molecular Formula: C14H27NO7
  • Molecular Weight: 321.367
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-07 08:28:10
  • Modify Date: 2024-01-08 05:10:13
  • Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
Synonyms 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
3,8,11,14-Tetraoxa-5-azaheptadecan-17-oic acid, 2,2-dimethyl-4-oxo-
Boc-9-AMino-4,7-Dioxanonanoic acid
t-Boc-N-amido-PEG3-acid
Description Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 471.1±40.0 °C at 760 mmHg
Molecular Formula C14H27NO7
Molecular Weight 321.367
Flash Point 238.7±27.3 °C
Exact Mass 321.178741
LogP 0.22
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.465
Hazard Codes Xn
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.