34399-44-5

34399-44-5 structure

Name: N-Demethyl-α-obscurine
Chemical Name: (1R,9S,10R,16R)-16-Methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadec-2(7)-en-5-one
CAS Number: 34399-44-5
Molecular Formula: C₁₆H₂₄N₂O
Molecular Weight: 260.375
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-07-19 11:23:47
Modify Date: 2024-01-30 20:29:43
N-Demethyl-α-obscurine, a lycodine-type Lycopodium alkaloid, is isolated from Lycopodii Herba[1].

Name	(1R,9S,10R,16R)-16-Methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadec-2(7)-en-5-one
Synonyms	(1R,9S,10R,16R)-16-Methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadec-2(7)-en-5-one 1H-5,10b-Propano-1,7-phenanthrolin-8(7H)-one, 2,3,4,4a,5,6,9,10-octahydro-12-methyl-, (4aR,5S,10bR,12R)-

Description	N-Demethyl-α-obscurine, a lycodine-type Lycopodium alkaloid, is isolated from Lycopodii Herba[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	N-Demethyl-α-obscurine exhibits Cmax (35.53 ng/mL), t1/2 (2.24 h), and AUC0→t (156.91 ng•h/mL) following i.g. administration (L. Herba extract; 4.8 g/kg) in rats[1].
References	[1]. Ma D, et, al. Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of Lycopodii Herba Extract by LC-MS/MS. Molecules. 2019 May 19;24(10):1930.