870487-48-2
870487-48-2 structure
- Name: Ms-PEG4-t-butyl ester
- Chemical Name: 2-Methyl-2-propanyl 3,6,9,12,15-pentaoxa-2-thiaoctadecan-18-oate 2,2-dioxide
- CAS Number: 870487-48-2
- Molecular Formula: C16H32O9S
- Molecular Weight: 400.485
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-20 12:16:11
- Modify Date: 2024-01-03 09:26:22
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Ms-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl 3,6,9,12,15-pentaoxa-2-thiaoctadecan-18-oate 2,2-dioxide |
|---|---|
| Synonyms |
MFCD20926382
2-Methyl-2-propanyl 3,6,9,12,15-pentaoxa-2-thiaoctadecan-18-oate 2,2-dioxide 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-[(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester |
| Description | Ms-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 499.9±40.0 °C at 760 mmHg |
| Molecular Formula | C16H32O9S |
| Molecular Weight | 400.485 |
| Flash Point | 256.1±27.3 °C |
| Exact Mass | 400.176697 |
| LogP | -0.13 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.460 |