105990-27-0
105990-27-0 structure
- Name: (S)-Higenamine hydrobromide
- Chemical Name: (1S)-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrobromide (1:1)
- CAS Number: 105990-27-0
- Molecular Formula: C16H18BrNO3
- Molecular Weight: 352.223
- Catalog: Research Areas Others
- Create Date: 2018-06-08 12:17:53
- Modify Date: 2024-01-29 15:57:07
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(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].
| Name | (1S)-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrobromide (1:1) |
|---|---|
| Synonyms |
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, (1S)-, hydrobromide (1:1)
(1S)-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrobromide (1:1) |
| Description | (S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1]. |
| References |
| Molecular Formula | C16H18BrNO3 |
|---|---|
| Molecular Weight | 352.223 |
| Exact Mass | 351.046997 |