1252257-56-9

1252257-56-9 structure

Name: SPDP-dPEG
Chemical Name: N-{27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
CAS Number: 1252257-56-9
Molecular Formula: C₃₁H₄₉N₃O₁₃S₂
Molecular Weight: 735.863
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-25 05:26:09
Modify Date: 2024-01-06 11:35:02
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

Name	N-{27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
Synonyms	Propanamide, N-[27-[(2,5-dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl]-3-(2-pyridinyldithio)- N-{27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide

Description	LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
References	[1]. Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.