1454619-13-6
1454619-13-6 structure
- Name: PU-H54
- Chemical Name: 8-((2,4-Dimethylphenyl)thio)-3-(pent-4-yn-1-yl)-3H-purin-6-amine
- CAS Number: 1454619-13-6
- Molecular Formula: C18H19N5S
- Molecular Weight: 337.442
- Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
- Create Date: 2018-06-22 14:57:46
- Modify Date: 2024-01-10 19:10:34
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PU-H54, a Grp94-selective inhibitor, can be used for the research of breast cancer. Hsp90 chaperone family, comprised in humans of four paralogs, Hsp90α, Hsp90β, Grp94 and Trap-1, has important roles in malignancy[1].
| Name | 8-((2,4-Dimethylphenyl)thio)-3-(pent-4-yn-1-yl)-3H-purin-6-amine |
|---|---|
| Synonyms |
8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine
3H-Purin-6-amine, 8-[(2,4-dimethylphenyl)thio]-3-(4-pentyn-1-yl)- 8-((2,4-Dimethylphenyl)thio)-3-(pent-4-yn-1-yl)-3H-purin-6-amine 8-[(2,4-Dimethylphenyl)sulfanyl]-3-(4-pentyn-1-yl)-3H-purin-6-amine PU-H54 |
| Description | PU-H54, a Grp94-selective inhibitor, can be used for the research of breast cancer. Hsp90 chaperone family, comprised in humans of four paralogs, Hsp90α, Hsp90β, Grp94 and Trap-1, has important roles in malignancy[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 475.0±55.0 °C at 760 mmHg |
| Molecular Formula | C18H19N5S |
| Molecular Weight | 337.442 |
| Flash Point | 241.1±31.5 °C |
| Exact Mass | 337.136108 |
| LogP | 2.30 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.663 |