1135131-50-8
1135131-50-8 structure
- Name: Bromo-PEG1-CH2COOH
- Chemical Name: (2-Bromoethoxy)acetic acid
- CAS Number: 1135131-50-8
- Molecular Formula: C4H7BrO3
- Molecular Weight: 183.001
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-27 00:22:52
- Modify Date: 2024-01-14 11:23:40
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Bromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1].
| Name | (2-Bromoethoxy)acetic acid |
|---|---|
| Synonyms |
MFCD20637665
Acetic acid, 2-(2-bromoethoxy)- (2-Bromoethoxy)acetic acid |
| Description | Bromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Christopher Michael Semko, et al. C26-linked rapamycin analogs as mtor inhibitors. WO2019212991A1. |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 316.4±17.0 °C at 760 mmHg |
| Molecular Formula | C4H7BrO3 |
| Molecular Weight | 183.001 |
| Flash Point | 145.2±20.9 °C |
| Exact Mass | 181.957855 |
| LogP | 0.22 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.493 |
| Hazard Codes | C |
|---|