1329611-28-0

1329611-28-0 structure

Name: Xanthurenic acid-d4
Chemical Name: 4,8-Dihydroxy-2-(2H4)quinolinecarboxylic acid
CAS Number: 1329611-28-0
Molecular Formula: C₁₀H₃D₄NO₄
Molecular Weight: 209.191
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-29 22:55:31
Modify Date: 2024-01-04 16:15:39
Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].

Name	4,8-Dihydroxy-2-(2H4)quinolinecarboxylic acid
Synonyms	2-Quinoline-3,5,6,7-d4-carboxylic acid, 4,8-dihydroxy- 4,8-Dihydroxy-2-(2H4)quinolinecarboxylic acid

Description	Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> GPCR/G Protein >> mGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Copeland CS, et al. Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42.