Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Boc-NH-PEG8-CH2CH2COOH
Price:
Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Boc-NH-PEG8-CH2CH2COOH
Price: ￥Inquiry/10g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

1334169-93-5

1334169-93-5 structure

1334169-93-5 structure

Name: Boc-NH-PEG8-CH2CH2COOH
Chemical Name: 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29-nonaoxa-5-azadotriacontan-32-oic acid
CAS Number: 1334169-93-5
Molecular Formula: C₂₄H₄₇NO₁₂
Molecular Weight: 541.630
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-29 11:21:03
Modify Date: 2024-01-09 15:56:37
Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29-nonaoxa-5-azadotriacontan-32-oic acid
Synonyms	2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29-nonaoxa-5-azadotriacontan-32-oic acid 3,8,11,14,17,20,23,26,29-Nonaoxa-5-azadotriacontan-32-oic acid, 2,2-dimethyl-4-oxo- MFCD13185254 t-Boc-N-amido-PEG8-acid

Description	Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.1±0.1 g/cm3
Boiling Point	627.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₄H₄₇NO₁₂
Molecular Weight	541.630
Flash Point	333.4±31.5 °C
Exact Mass	541.309814
LogP	-1.58
Vapour Pressure	0.0±4.0 mmHg at 25°C
Index of Refraction	1.468

Hazard Codes	Xi