137160-11-3

137160-11-3 structure

Name: Aptiganel hydrochloride
Chemical Name: Aptiganel
CAS Number: 137160-11-3
Molecular Formula: C₂₀H₂₂ClN₃
Molecular Weight: 303.401
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2018-06-15 02:19:51
Modify Date: 2024-01-12 10:46:23
Aptiganel hydrochloride (Cerestat) is a non-competitive NMDA receptor antagonist with neuroprotective effect.

Name	Aptiganel
Synonyms	1-(3-ethylphenyl)-1-methyl-3-naphthalen-1-ylguanidine 1-(3-Ethylphenyl)-1-methyl-2-(1-naphthyl)guanidine N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine 46475LV84I Guanidine, N-(3-ethylphenyl)-N-methyl-N''-1-naphthalenyl- Aptiganel

Description	Aptiganel hydrochloride (Cerestat) is a non-competitive NMDA receptor antagonist with neuroprotective effect.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Kroppenstedt SN, Schneider GH, Thomale UW, Unterberg AW. Neuroprotective properties of aptiganel HCL (Cerestat) following controlled cortical impact injury. Acta Neurochir Suppl. 1998;71:114-116. [2]. McBurney RN. Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury. Int Rev Neurobiol. 1997;40:173-195.