287174-32-7
287174-32-7 structure
- Name: Hydroxy-PEG1-CH2-Boc
- Chemical Name: 2-Methyl-2-propanyl (2-hydroxyethoxy)acetate
- CAS Number: 287174-32-7
- Molecular Formula: C8H16O4
- Molecular Weight: 176.210
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-03 08:05:30
- Modify Date: 2024-01-16 20:40:56
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Hydroxy-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl (2-hydroxyethoxy)acetate |
|---|---|
| Synonyms |
2-Methyl-2-propanyl (2-hydroxyethoxy)acetate
Acetic acid, 2-(2-hydroxyethoxy)-, 1,1-dimethylethyl ester MFCD27635155 |
| Description | Hydroxy-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 257.0±15.0 °C at 760 mmHg |
| Molecular Formula | C8H16O4 |
| Molecular Weight | 176.210 |
| Flash Point | 95.2±13.9 °C |
| Exact Mass | 176.104858 |
| LogP | 0.83 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.438 |
| Hazard Codes | Xi |
|---|