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850090-13-0

850090-13-0 structure
850090-13-0 structure
  • Name: Tos-PEG2-C2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 3-[2-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]propanoate
  • CAS Number: 850090-13-0
  • Molecular Formula: C18H28O7S
  • Molecular Weight: 388.476
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-15 00:42:02
  • Modify Date: 2024-01-09 20:09:38
  • Tos-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 3-[2-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]propanoate
Synonyms Propanoic acid, 3-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3-[2-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]propanoate
MFCD27635184
Tos-PEG2-C2-Boc
Description Tos-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Density 1.2±0.1 g/cm3
Boiling Point 495.2±35.0 °C at 760 mmHg
Molecular Formula C18H28O7S
Molecular Weight 388.476
Flash Point 253.3±25.9 °C
Exact Mass 388.155579
LogP 2.45
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.498
Storage condition 2-8℃
Hazard Codes Xn