Name | Disodium {1,4-phenylenebis[2-ethyl-1-ylidene(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl-3-ylidene)]}dimethanesulfonate |
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Synonyms |
Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedi-2-ethyl-1-ylidene)bis[7,7-dimethyl-2-oxo-, sodium salt (1:2)
Disodium {1,4-phenylenebis[2-ethyl-1-ylidene(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl-3-ylidene)]}dimethanesulfonate L55 A CVYTJ A1 A1 B1SWQ DU2R D2U- DL55 A CVYTJ A1 A1 B1SWQ &&2Na salt |
Description | Ecamsule disodium is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression[1][2]. |
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Related Catalog | |
In Vitro | Ecamsule is a broad-spectrum UVA-absorber with maximum absorbance at 344 nm[1]. Wild-type Fibs E6/E7 cells are more sensitive towards Ecamsule (200-1600 μM) treatment. In the fibroblasts, Ecamsule counteractes UV and AAPH induced ROS-formation. In addition, basal ROS levels are reduced. The effects are dose-dependent, reaching a maxi-mum ROS reduction by 25.7% at the highest tested concentration of 1600 μM in the UV-setting. With the same concentration of Ecamsule, oxidative stress that had been trigged by AAPH is reduced by 10.8% and basal levels are attenuated by 16.9%. Ecamsule increases the viability at the highest applied concentration of 1600 μM in the AAPH-treated cells[1]. |
References |
Molecular Formula | C30H36Na2O8S2 |
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Molecular Weight | 634.712 |
Exact Mass | 634.164673 |