1034297-58-9
1034297-58-9 structure
- Name: CRT5
- Chemical Name: 3-[6-Amino-5-(6-ethoxy-2-naphthyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide
- CAS Number: 1034297-58-9
- Molecular Formula: C28H30N4O2
- Molecular Weight: 454.563
- Catalog: Signaling Pathways Apoptosis PKD
- Create Date: 2018-06-13 16:39:52
- Modify Date: 2024-01-08 18:59:20
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CRT5, a pyrazine benzamide, is a potent and selective inhibitor for all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively). CRT5 decreases VEGF-induced endothelial migration, proliferation and tubulogenesis[1].
| Name | 3-[6-Amino-5-(6-ethoxy-2-naphthyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide |
|---|---|
| Synonyms |
Benzamide, 3-[6-amino-5-(6-ethoxy-2-naphthalenyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]-
MFCD29081160 3-[6-Amino-5-(6-ethoxy-2-naphthyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide CRT5 |
| Description | CRT5, a pyrazine benzamide, is a potent and selective inhibitor for all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively). CRT5 decreases VEGF-induced endothelial migration, proliferation and tubulogenesis[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 651.2±55.0 °C at 760 mmHg |
| Molecular Formula | C28H30N4O2 |
| Molecular Weight | 454.563 |
| Flash Point | 347.6±31.5 °C |
| Exact Mass | 454.236877 |
| LogP | 5.22 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.632 |