1245823-50-0

1245823-50-0 structure

Name: Propargyl-PEG4-CH2CH2-Boc
Chemical Name: 2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
CAS Number: 1245823-50-0
Molecular Formula: C₁₈H₃₂O₇
Molecular Weight: 360.443
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-07-11 13:11:02
Modify Date: 2024-01-31 09:15:01
Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].

Name	2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
Synonyms	MFCD22201534 2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate 4,7,10,13,16-Pentaoxanonadec-18-yn-1-oic acid, 1,1-dimethylethyl ester

Description	Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.

Hazard Codes	Xi