1628214-07-2
1628214-07-2 structure
- Name: CPI-4203
- Chemical Name: 6-Ethyl-5-(2-methylphenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
- CAS Number: 1628214-07-2
- Molecular Formula: C16H14N4O
- Molecular Weight: 278.309
- Catalog: Signaling Pathways Epigenetics Histone Demethylase
- Create Date: 2018-06-08 14:38:53
- Modify Date: 2024-01-11 01:07:47
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CPI-4203 is a potent KDM5A inhibitor with an IC50 of 250 nM. CPI-4203 is competitive with 2-oxoglutarate (2-OG). CPI-4203 is structurally related to CPI-455 (HY-100421) but is less potent[1].
| Name | 6-Ethyl-5-(2-methylphenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile |
|---|---|
| Synonyms |
6-Ethyl-5-(2-methylphenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 6-ethyl-4,7-dihydro-5-(2-methylphenyl)-7-oxo- |
| Description | CPI-4203 is a potent KDM5A inhibitor with an IC50 of 250 nM. CPI-4203 is competitive with 2-oxoglutarate (2-OG). CPI-4203 is structurally related to CPI-455 (HY-100421) but is less potent[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 250 nM (KDM5A)[1] |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 499.4±55.0 °C at 760 mmHg |
| Molecular Formula | C16H14N4O |
| Molecular Weight | 278.309 |
| Flash Point | 255.8±31.5 °C |
| Exact Mass | 278.116760 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.670 |