18887-18-8

18887-18-8 structure

Name: Hydroxytanshinone IIA
Chemical Name: 9-Hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
CAS Number: 18887-18-8
Molecular Formula: C₁₉H₁₈O₄
Molecular Weight: 310.344
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2018-07-07 06:36:08
Modify Date: 2024-01-02 08:12:09
Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].

Name	9-Hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
Synonyms	9-Hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-9-hydroxy-1,6,6-trimethyl-

Description	Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. Peng Li, et al. Simultaneous determination of tanshinone IIA and its three hydroxylated metabolites by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(5):815-22.

Hazard Codes	Xi