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1312309-62-8

1312309-62-8 structure
1312309-62-8 structure
  • Name: Ms-PEG2-C2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 3,6,9-trioxa-2-thiadodecan-12-oate 2,2-dioxide
  • CAS Number: 1312309-62-8
  • Molecular Formula: C12H24O7S
  • Molecular Weight: 312.380
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-01 17:59:47
  • Modify Date: 2024-01-16 15:17:39
  • Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 3,6,9-trioxa-2-thiadodecan-12-oate 2,2-dioxide
Synonyms Propanoic acid, 3-[2-[2-[(methylsulfonyl)oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3,6,9-trioxa-2-thiadodecan-12-oate 2,2-dioxide
MFCD20926372
Description Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 429.2±30.0 °C at 760 mmHg
Molecular Formula C12H24O7S
Molecular Weight 312.380
Flash Point 213.4±24.6 °C
Exact Mass 312.124268
LogP 0.58
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.456