Ms-PEG2-C2-Boc

Modify Date: 2024-01-16 15:17:39

Ms-PEG2-C2-Boc Structure
Ms-PEG2-C2-Boc structure
Common Name Ms-PEG2-C2-Boc
CAS Number 1312309-62-8 Molecular Weight 312.380
Density 1.2±0.1 g/cm3 Boiling Point 429.2±30.0 °C at 760 mmHg
Molecular Formula C12H24O7S Melting Point N/A
MSDS N/A Flash Point 213.4±24.6 °C

 Use of Ms-PEG2-C2-Boc


Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 3,6,9-trioxa-2-thiadodecan-12-oate 2,2-dioxide
Synonym More Synonyms

 Ms-PEG2-C2-Boc Biological Activity

Description Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 429.2±30.0 °C at 760 mmHg
Molecular Formula C12H24O7S
Molecular Weight 312.380
Flash Point 213.4±24.6 °C
Exact Mass 312.124268
LogP 0.58
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.456

 Synonyms

Propanoic acid, 3-[2-[2-[(methylsulfonyl)oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3,6,9-trioxa-2-thiadodecan-12-oate 2,2-dioxide
MFCD20926372
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