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1312309-63-9

1312309-63-9 structure
1312309-63-9 structure
  • Name: Azido-PEG2-C2-acid
  • Chemical Name: 3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
  • CAS Number: 1312309-63-9
  • Molecular Formula: C7H13N3O4
  • Molecular Weight: 203.196
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-04 16:22:57
  • Modify Date: 2024-01-21 12:01:26
  • Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
Synonyms Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-
3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
MFCD20926378
Azido-PEG2-acid
Azido-PEG3-acid
Description Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H13N3O4
Molecular Weight 203.196
Exact Mass 203.090607
LogP -0.35