Azido-PEG2-C2-acid

Modify Date: 2024-01-21 12:01:26

Azido-PEG2-C2-acid Structure
Azido-PEG2-C2-acid structure
Common Name Azido-PEG2-C2-acid
CAS Number 1312309-63-9 Molecular Weight 203.196
Density N/A Boiling Point N/A
Molecular Formula C7H13N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-C2-acid


Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
Synonym More Synonyms

 Azido-PEG2-C2-acid Biological Activity

Description Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H13N3O4
Molecular Weight 203.196
Exact Mass 203.090607
LogP -0.35

 Synonyms

Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-
3-[2-(2-Azidoethoxy)ethoxy]propanoic acid
MFCD20926378
Azido-PEG2-acid
Azido-PEG3-acid
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