1334170-01-2

1334170-01-2 structure

Name: Bis-PEG7-PFP ester
Chemical Name: Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate
CAS Number: 1334170-01-2
Molecular Formula: C₃₀H₃₂F₁₀O₁₁
Molecular Weight: 758.552
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-09 03:14:01
Modify Date: 2024-01-09 18:24:39
Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate
Synonyms	4,7,10,13,16,19,22-Heptaoxapentacosane-1,25-dioic acid, bis(2,3,4,5,6-pentafluorophenyl) ester Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate

Description	Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.