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1334170-01-2

1334170-01-2 structure
1334170-01-2 structure
  • Name: Bis-PEG7-PFP ester
  • Chemical Name: Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate
  • CAS Number: 1334170-01-2
  • Molecular Formula: C30H32F10O11
  • Molecular Weight: 758.552
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-09 03:14:01
  • Modify Date: 2024-01-09 18:24:39
  • Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate
Synonyms 4,7,10,13,16,19,22-Heptaoxapentacosane-1,25-dioic acid, bis(2,3,4,5,6-pentafluorophenyl) ester
Bis(pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosane-1,25-dioate
Description Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.4±0.1 g/cm3
Boiling Point 664.2±55.0 °C at 760 mmHg
Molecular Formula C30H32F10O11
Molecular Weight 758.552
Flash Point 342.1±26.4 °C
Exact Mass 758.178467
LogP 2.84
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.465