1482500-76-4
1482500-76-4 structure
- Name: ML-290
- Chemical Name: ML290
- CAS Number: 1482500-76-4
- Molecular Formula: C24H21F3N2O5S
- Molecular Weight: 506.49
- Catalog: Research Areas Others
- Create Date: 2018-07-21 11:12:20
- Modify Date: 2024-01-01 21:15:33
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ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].
| Name | ML290 |
|---|---|
| Synonyms |
MFCD28118984
Benzamide, 2-(1-methylethoxy)-N-[2-[[[3-[(trifluoromethyl)sulfonyl]phenyl]amino]carbonyl]phenyl]- 2-Isopropoxy-N-[2-({3-[(trifluoromethyl)sulfonyl]phenyl}carbamoyl)phenyl]benzamide ML290 ML-290 |
| Description | ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 94 nM (RXFP1)[1] |
| In Vitro | ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 (5 μM) shows anti-fibrotic, relaxin-like gene expression at 24 and 72 h in activated human hepatic stellate cells[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 523.5±50.0 °C at 760 mmHg |
| Molecular Formula | C24H21F3N2O5S |
| Molecular Weight | 506.49 |
| Flash Point | 270.4±30.1 °C |
| Exact Mass | 506.112335 |
| LogP | 5.00 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.590 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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