ML-290

Modify Date: 2024-01-01 21:15:33

ML-290 Structure
ML-290 structure
Common Name ML-290
CAS Number 1482500-76-4 Molecular Weight 506.49
Density 1.4±0.1 g/cm3 Boiling Point 523.5±50.0 °C at 760 mmHg
Molecular Formula C24H21F3N2O5S Melting Point N/A
MSDS Chinese USA Flash Point 270.4±30.1 °C

 Use of ML-290


ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].

 Names

Name ML290
Synonym More Synonyms

 ML-290 Biological Activity

Description ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].
Related Catalog
Target

EC50: 94 nM (RXFP1)[1]

In Vitro ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 (5 μM) shows anti-fibrotic, relaxin-like gene expression at 24 and 72 h in activated human hepatic stellate cells[1].
References

[1]. Wilson KJ, et al. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile. Eur J Med Chem. 2018 Aug 5;156:79-92.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 523.5±50.0 °C at 760 mmHg
Molecular Formula C24H21F3N2O5S
Molecular Weight 506.49
Flash Point 270.4±30.1 °C
Exact Mass 506.112335
LogP 5.00
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.590
Storage condition 2-8℃

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

MFCD28118984
Benzamide, 2-(1-methylethoxy)-N-[2-[[[3-[(trifluoromethyl)sulfonyl]phenyl]amino]carbonyl]phenyl]-
2-Isopropoxy-N-[2-({3-[(trifluoromethyl)sulfonyl]phenyl}carbamoyl)phenyl]benzamide
ML290
ML-290
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: ML-290
  • Price: $750.0/100mg $1500.0/250mg $3000.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: ¥2500/5 mg

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